digest – Page 2 – Tech Today w/ Ken May

Risky stem cell treatment reverses MS in 70% of patients in small study

MS brain lesion as seen on an MRI. (credit: James Heilman, MD ) By obliterating the broken immune systems of patients with severe forms of multiple sclerosis, then sowing fresh, defect-free systems with transplanted stem cells, researchers can thwart the degenerative autoimmune disease—but it comes at a price. In a small phase II trial of 24 MS patients, the treatment halted or reversed the disease in 70 percent of patients for three years after the transplant. Eight patients saw that improvement last for seven and a half years, researchers report in the Lancet . This means that some of those patients went from being wheelchair-bound to walking and being active again. But to reach that success, many suffered through severe side effects, such as life threatening infections and organ damage from toxicity brought on by the aggressive chemotherapy required to annihilate the body’s immune system. One patient died from complications of the treatment, which represents a four percent fatality rate. Moreover, while the risks may be worthwhile to some patients with rapidly progressing forms of MS—a small percentage of MS patients—the researchers also caution that the trial was small and did not include a control group. Read 7 remaining paragraphs | Comments

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Risky stem cell treatment reverses MS in 70% of patients in small study

Verizon could rule the ’90s cyberscape as owner of both AOL and Yahoo

Yahoo’s once-iconic San Francisco billboard, pictured here in 2011. (credit: Scott Schiller ) Verizon is submitting a $3 billion (£2 billion) bid to purchase Yahoo’s core Internet business, according to The Wall Street Journal , which cites an anonymous source. Though at least one more round of bidding is expected, Verizon is reportedly the leading contender. A Verizon spokesperson declined comment when contacted by Ars this morning. Yahoo has been shopping itself around for months in an attempt to sell off just about everything except its valuable stake in Chinese e-commerce company Alibaba. Yahoo is also looking to sell other assets including real estate and patents, but Verizon reportedly isn’t interested in buying those. Read 2 remaining paragraphs | Comments

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Verizon could rule the ’90s cyberscape as owner of both AOL and Yahoo

Kraftwerk loses hip-hop music-sampling copyright case

(credit: Tobias Helfrich ) After a decades-long battle, the Bundesverfassungsgericht (the supreme German Constitutional Court) has overturned a ban on a song that used a two-second sample of a Kraftwerk recording. In 1997, music producer Moses Pelham used a clip from 1977 release Metall auf Metall (Metal on Metal) in the song Nur mir (Only Mine) performed by Sabrina Setlur. Lead singer of Kraftwerk, Ralf Huetter, sued Pelham, and in 2012 the electropop pioneer won his case for copyright infringement in Germany’s Federal Court of Justice (Bundesgerichtshof), gaining damages and a block on Nur mir . However, in today’s judgment, the eight judges of the First Senate of the Federal Constitutional Court decided that the lower court did not sufficiently consider whether the impact of the sample on Krafwerk might be “negligible.” Read 5 remaining paragraphs | Comments

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Kraftwerk loses hip-hop music-sampling copyright case

AT&T’s data caps impose harshest punishments on DSL users

(credit: Mike Mozart ) AT&T’s home Internet data caps got an overhaul yesterday when the company implemented a recently announced plan to strictly enforce the caps and collect overage fees from more customers. Customers stuck on AT&T’s older DSL architecture will be facing lower caps and potentially higher overage fees than customers with more modern Internet service. AT&T put a positive spin on the changes when it announced them in March , saying that it was increasing the monthly data limits imposed on most home Internet customers. This was technically true as AT&T already had caps for most Internet users. But previously, the caps were only enforced in DSL areas, so the limits had no financial impact on most customers. Now, a huge swath of AT&T customers have effectively gone from unlimited plans to ones that are capped, with an extra $10 charge for each additional 50GB of data provided per month. The only customers who aren’t getting an increase in their monthly data allowance are the ones who have been dealing with caps the past few years, according to AT&T’s data usage website : Read 7 remaining paragraphs | Comments

1.5 billion-year-old fossils reveal organisms of unusual size

Just a couple of 1.56 billion-year-old fossils from southern China. (credit: Maoyan Zhu) The Cambrian “explosion” of life around 540 million years ago is one heck of a story, in which a huge variety of animal body plans first appear in the fossil record. But the harder we look, the more interesting and incredible the Cambrian prequels become. Now, there’s a report of organisms big enough to be easily visible yet dating back to more than 1.5 billion years ago. The fuse to the Cambrian bomb was quite long and, at the very least, had some firecrackers tied to it. Single-celled eukaryotes, organisms with a nucleus and other complex internal structures, joined the bacteria and archaea around 1.5 billion years before the Cambrian. About 60 million years before the start of the Cambrian, a considerable batch of complex organisms appeared, although their relationships to Cambrian life are contentious. The history of multi-cellular eukaryotes in between is hard to piece together, as extraordinary luck is needed to preserve evidence of their soft cell bodies for us to find. We have a couple examples of tiny multi-cellular organisms that may have been eukaryotes, but a new discovery from a team led by Shixing Zhu of the China Geological survey adds a big one to the family. The long, flat fossils they found in 1.56 billion-year-old rocks were up to a whopping 30 centimeters long and 8 centimeters wide. Read 5 remaining paragraphs | Comments

This 1996 Sega training video is the most ‘90s thing you’ll see this week

This internal Sega video for testers is a wonderful snapshot of the ’90s. If you’ve ever wondered what Sega was like at the height of its game-making powers, wonder no more. A staff video from the Sega vaults—made in 1996, the same year that the Sony PlayStation would begin to take over the world—has been released by the production company behind it, Green Mill Filmworks . Not only is the video a fascinating behind-the scenes look at game development and game testing, it is also, without doubt, the most ’90s thing I’ve ever seen. Even excluding the baggy clothes, questionable hair cuts, and horrifying denim, the desks of game testers interviewed—many of whom said they worked up to 90 hours a week squashing bugs—are littered with ’90s paraphernalia. My personal favourite, aside from the multiple appearances of the obligatory (for the ’90s at least) Jurassic Park merchandise, is the spinning holographic disk that appears 13 minutes in. I had one of those as a kid, and while I still don’t quite understand what the appeal was, they were all the rage at school, even over here in the UK. Of course, there’s lots of Sega tech on show too, with testers having access to the Mega Drive (Genesis to our US friends), 32X, Sega CD, Game Gear, Saturn, and even the short-lived Sega Pico, a laptop-like educational system for kids that was powered by Genesis hardware. Each tester was also issued with development cartridges—which you can see being loaded up with memory chips by hand around 18 minutes in—before having to sit and play the game relentlessly, using a VHS recorder (yes really) to record gameplay and identify when and how bugs appeared. Read 9 remaining paragraphs | Comments

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This 1996 Sega training video is the most ‘90s thing you’ll see this week

Uber to begin testing self-driving cars in Pittsburgh

(credit: Uber) One day, the Uber that comes to fetch you might not have anyone in the driver’s seat. On Thursday, Uber announced that it will begin testing an autonomous Ford Fusion hybrid on the streets of Pittsburgh, home to Uber’s Advanced Technology Center. Drivers in Pittsburgh should have no problem spotting the research vehicle—it’s carrying an array of sensors on its roof that includes a radar, lidar, and cameras. The Uber test car will actually be mapping its surroundings in addition to testing out autonomous driving—although there will be a human operator in the driver’s seat at all times to take over at a moment’s notice. We’ve known for some time that Uber has had an interest in autonomous vehicles. In the past, the company had been working with Google, but that relationship apparently deteriorated last year . It’s not the only ride-sharing service looking to ditch the human aspect, either. In January, we reported that General Motors invested $500 million in Lyft with the goal of developing a network of self-driving taxis. Read 2 remaining paragraphs | Comments

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Uber to begin testing self-driving cars in Pittsburgh

“Mega Cable” is here, as Charter finalizes purchase of TWC

(credit: Cole Marshall ) Charter Communications today said it has closed its acquisitions of Time Warner Cable and Bright House Networks following approvals from the Federal Communications Commission and regulators in California , the final state that had to sign off on the deal. Charter has nearly quadrupled in size as a result of the transactions, going from 6.8 million customers to about 25.4 million in 41 states, second in the US after Comcast’s 28 million. The merger drew opposition from some advocacy groups, including one that took to calling the new Charter ” Mega Cable .” The cost of the acquisitions was originally expected to be about $67.1 billion, though Charter will reportedly end up paying a bit more than that. Charter’s announcement today said, “The completion of the transactions will drive investment into the combined entity’s advanced broadband network, resulting in faster broadband speeds, better video products, more affordable phone service, and more competition for consumers and businesses.” Read 4 remaining paragraphs | Comments

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“Mega Cable” is here, as Charter finalizes purchase of TWC

Windows 7 now has a Service Pack 2 (but don’t call it that)

This should become a thing of the past. (credit: Microsoft ) Anyone who’s installed Windows 7 any time in the last, oh, five years or so probably didn’t enjoy the experience very much. Service Pack 1 for the operating system was released in 2011, meaning that a fresh install has five years of individual patches to download and install. Typically, this means multiple trips to Windows Update and multiple reboots in order to get the system fully up-to-date, and it is a process that is at best tedious, typically leading one to wonder why, at the very least, it cannot pull down all the updates at once and apply them with just a single reboot. The answer to that particular question will, unfortunately, remain a mystery, but Microsoft did today announce a change that will greatly reduce the pain of this process. The company has published a “convenience rollup” for Windows 7 Service Pack 1 (and Windows Server 2008 R2), which in a single package contains all the updates, both security and non-security, released since the Service Pack, up through April 2016. Installing the rollup will perform five years of patching in one shot. In other words, it performs a very similar role to what Windows 7 Service Pack 2 would have done, if only Windows 7 Service Pack 2 were to exist. It’s not quite the same as a Service Pack—it still requires Service Pack 1 to be installed, and the system will still report that it is running Service Pack 1—but for most intents and purposes, that won’t matter. Microsoft will also support injecting this rollup into Windows 7 Service Pack 1 system images and install media. Read 5 remaining paragraphs | Comments

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Windows 7 now has a Service Pack 2 (but don’t call it that)

iOS 9.3.2 is here, fixes iPhone SE Bluetooth problems and other bugs

(credit: Andrew Cunningham) Apple has just released iOS 9.3.2, a minor update to iOS 9 that fixes a handful of minor bugs. The most significant fix is related to the iPhone SE, which ” could experience audio quality issues ” when paired to Bluetooth headsets. The full release notes are below: Fixes an issue where some Bluetooth accessories could experience audio quality issues when paired to the iPhone SE Fixes an issue where looking up dictionary definitions could fail Addresses an issue that prevented typing email addresses when using the Japanese Kana keyboard in Mail and Messages Fixes an issue for VoiceOver users using the Alex voice, where the device switches to a different voice to announce punctuation or spaces Fixes an issue that prevented MDM servers from installing Custom B2B apps All of these fixes are for minor edge cases that affect only small fractions of the iOS userbase—major development on iOS 9 stopped with iOS 9.3 , at which point Apple presumably shifted its focus to the new version of iOS that we’ll see at WWDC next month. The update is available for all devices that support iOS 9, including the iPhone 4S and newer; iPad 2 and newer; all iPad Minis and iPad Pros; and the fifth- and sixth-generation iPod Touches. Apple also released minor updates for its other iOS-derived platforms, the Apple Watch and the fourth-generation Apple TV. The release notes for watchOS 2.2.1 and tvOS 9.2.1 don’t name any specific fixes, but if you want the latest “bug fixes and security updates” you can download both of them now. Read on Ars Technica | Comments

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iOS 9.3.2 is here, fixes iPhone SE Bluetooth problems and other bugs