Using synthetic nervous system, paralyzed man is first to move again

(credit: Ohio State University Wexner Medical Center/ Batelle ) With a paralyzing spinal cord injury, the biological wiring that hooks up our controlling brains to our useful limbs gets snipped, leading to permanent loss of sensation and control and usually a lifetime of extra health care. Researchers have spent years working to repair those lost connections, allowing paralyzed patients to  sip coffee and enjoy a beer with robotic limbs controlled by just their minds. Now, researchers have gone a step further, allowing a paralyzed person to control his own hand with just his mind. In a study published Wednesday in Nature, researchers report using a “ neural bypass ” that reconnects a patient’s mental commands for movement to responsive muscles in his limbs, creating somewhat of a synthetic nervous system. The pioneering patient, Ian Burkhart, a 24-year-old man left with quadriplegia after a diving accident almost six years ago, can once again move his hand. In the pilot study he could control movement of individual fingers, grasp big and small objects, swipe a credit card, and play Guitar Hero . The advance may open the door to restorative treatments for paralyzed individuals, allowing them to have independent movement—and lives. Read 10 remaining paragraphs | Comments

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Using synthetic nervous system, paralyzed man is first to move again

Nvidia unveils first Pascal graphics card, the monstrous Tesla P100

The first full-fat GPU based on Nvidia’s all-new Pascal architecture is here. And while the Tesla P100 is aimed at professionals and deep learning systems rather than consumers, if consumer Pascal GPUs are anything like it—and there’s a very good chance they will be—gamers and enthusiasts alike are going to see a monumental boost in performance. The  Tesla P100 is the first full-size Nvidia GPU based on the TSMC 16nm FinFET manufacturing process—like AMD, Nvidia has been stuck using an older 28nm process since 2012—and the first to feature the second generation of High Bandwidth Memory (HBM2). Samsung began mass production of faster and higher capacity HBM2 memory back in January. While recent rumours suggested that both Nvidia and AMD wouldn’t use HMB2 this year due to it being prohibitively expensive—indeed, AMD’s recent roadmap suggests that its new Polaris GPUs won’t use HBM2 —Nvidia has at least taken the leap with its professional line of GPUs. The result of the P100’s more efficient manufacturing process, architecture upgrades, and HBM2 is a big boost in performance over Nvidia’s current performance champs like the Maxwell-based Tesla M40 and the Titan X/Quadro M6000. Nvidia says the P100 reaches 21.2 teraflops of half-precision (FP16) floating point performance, 10.6 teraflops of single precision (FP32), and 5.3 teraflops (1/2 rate) of double precision. By comparison, the Titan X and Tesla M40 offer just 7 teraflops of single precision floating point performance. Read 9 remaining paragraphs | Comments

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Nvidia unveils first Pascal graphics card, the monstrous Tesla P100

A spiritual successor to Aaron Swartz is angering publishers all over again

Aaron Swartz would be proud of Alexandra Elbakyan. The 27-year-old is at the center of a lawsuit brought by a leading science publisher that is labeling her a hacker and infringer. (credit: Courtesy of Alexandra Elbakyan) Stop us if you’ve heard this before: a young academic with coding savvy has become frustrated with the incarceration of information. Some of the world’s best research continues to be trapped behind subscriptions and paywalls. This academic turns activist, and this activist then plots and executes the  plan. It’s time to free information from its chains—to give it to the masses free of charge. Along the way, this research Robin Hood is accused of being an illicit, criminal hacker. This, of course, describes the tale of the late Aaron Swartz . His situation captured the Internet’s collective attention as the data crusader attacked research paywalls. Swartz was notoriously charged as a hacker for trying to free millions of articles from popular academic hub JSTOR. At age 26, he tragically committed suicide just ahead of his federal trial in 2013. But suddenly in 2016, the tale has new life.  The Washington Post   decries it as academic research’s Napster moment, and it all stems from a 27-year-old bioengineer turned Web programmer from Kazakhstan (who’s living in Russia). Just as Swartz did, this hacker is freeing tens of millions of research articles from paywalls, metaphorically hoisting a middle finger to the academic publishing industry, which, by the way, has again reacted with labels like “hacker” and “criminal.” Read 30 remaining paragraphs | Comments

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A spiritual successor to Aaron Swartz is angering publishers all over again

Reddit removes “warrant canary” from its latest transparency report

(credit: Cyrus Farivar) Reddit has removed the warrant canary posted on its website, suggesting that the company may have been served with some sort of secret court order or document for user information. At the bottom of its 2014 transparency report , the company wrote: “As of January 29, 2015, reddit has never received a National Security Letter, an order under the Foreign Intelligence Surveillance Act, or any other classified request for user information. If we ever receive such a request, we would seek to let the public know it existed.” That language was conspicuously missing from the 2015 transparency report that was published Thursday morning. Read 3 remaining paragraphs | Comments

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Reddit removes “warrant canary” from its latest transparency report

New ransomware installs in boot record, encrypts hard disk [Updated]

Yet another harsh lesson for people who click things they shouldn’t. A new type of malware has been described, one that takes crypto-extortion to a new level. While most cryptographic ransomware variants are selective about what they encrypt—leaving the computer usable to make it easier for the victim to pay—this new entry targets the victim’s entire startup drive, encrypting the master file table (MFT). Called Petya, the new ransomware is just the latest ransomware deliberately tailored for victims within organizations with IT support instead of a broader audience.  As BleepingComputer’s Lawrence Abrams documented , Petya is currently being delivered via Dropbox links in e-mail messages targeting human resources departments at companies in Germany. The links are purported to be to an application to be installed by the HR employee. Running the attachment throws up a Windows alert; if the user clicks to continue, Petya is inserted into the master boot record (MBR) of the victim’s computer, and the system restarts. On reboot, the malware performs a fake Windows CHKDSK, warning “One of your disks contains errors and needs to be repaired,” Petya then flashes up an ASCII skull and crossbones on a red and white screen, announcing “You became victim of the PETYA RANSOMWARE!” Read 3 remaining paragraphs | Comments

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New ransomware installs in boot record, encrypts hard disk [Updated]

Cops: Lottery terminal hack allowed suspects to print more winning tickets

Six people have been charged in what prosecutors say was a scheme to hack Connecticut state lottery terminals so they produced more winning tickets and fewer losing ones. At least two of the suspects have been charged with felonies, including first-degree larceny, first-degree computer crimes, and rigging a game, according to an article published by The Hartford Courant . The suspects allegedly owned or worked at retail stores that produced winning tickets in numbers that were much higher than the state average. Of tickets generated at one liquor store, for instance, 76 percent were instant winners in one sample and 59 percent in another sample. The state-wide average, meanwhile, was just 24 percent. After manipulating the terminals, the suspects cashed the tickets and took the proceeds, prosecutors alleged. The charges come several months after lottery officials suspended a game called the 5 Card Cash after they noticed it was generating more winning tickets than its parameters should have allowed. The game remains suspended. Investigators say more arrests may be made in the future. Almost a year ago, prosecutors in Iowa presented evidence indicating the former head of computer security for the state’s lottery association tampered with lottery computers prior to buying a ticket that won a $14.3 million jackpot. Read 2 remaining paragraphs | Comments

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Cops: Lottery terminal hack allowed suspects to print more winning tickets

Minimalist genome—only 473 genes—synthesized and used to boot up a cell

The bacteria that acted as the raw material for this experiment. Life is a rather difficult thing to define, but there are a few aspects that most biologists would agree on: it has to maintain genetic material and be able to make copies of itself. Both of these require energy, so it also must host some sort of minimal metabolism. In large, complex cells, each of these requirements takes hundreds of genes. Even in the simplified genomes of some bacteria, the numbers are still over a hundred. But does this represent the minimum number of genes that life can get away with? About a decade ago, researchers started to develop the technology to synthesize a genome from scratch and then put it in charge of a living cell. Now, five years after their initial successes, researchers used this model to try to figure out the genetic minimum for life itself. At first, the project seemed to be progressing well. In 2008, the team described the tools it had developed that could build the entire genome of a bacterium. (The team used a parasitic bacteria called Mycoplasma genitalium that started with only 525 genes.) Two years after that, they managed to get a genome synthesized using this method to boot up bacteria , taking the place of the normal genome. Read 15 remaining paragraphs | Comments

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Minimalist genome—only 473 genes—synthesized and used to boot up a cell

London to NYC in just 3.4 hours? A roundtrip will set you back $5,000

An artist’s conception of the Boom aircraft at London’s Heathrow Airport. (credit: Boom) After more than a decade of dormancy commercial supersonic flight may soon return to the skies. The Soviet Tupolev supersonic aircraft flew just a few dozen flights back in 1977, and the Concorde, flown by British Airways and Air France, retired in 2003 after a fatal accident three years earlier that compounded economic problems. But now Richard Branson and his Virgin empire are ready to try it again. According to   The Guardian , Branson has signed a deal with an American firm to bring commercial supersonic travel to the airways, beginning with trans-Atlantic flights between London and New York City. The agreement brings Branson’s Virgin Galactic into a partnership with Colorado-based Boom, founded by Amazon executive Blake Scholl. Virgin Galactic, according to a company spokeswoman, will provide engineering, design, operations, and manufacturing services, along with flight tests at Virgin’s base in Mojave, Calif. It will then have an option to buy the first 10 airframes from Boom. Read 8 remaining paragraphs | Comments

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London to NYC in just 3.4 hours? A roundtrip will set you back $5,000

10 more OEMs pledge to make auto-braking standard in new cars

(credit: Ford) The number of car makers committed to making automatic emergency braking a standard feature on all new cars has doubled this week. On Thursday the National Highway Traffic Safety Administration and the Insurance Institute for Highway Safety announced that 20 manufacturers are now onboard with the plan, which will see AEB systems installed throughout their model range by 2022. In September of last year, we reported that 10 OEMs had already made the pledge. In the past, government mandates were needed to spread advanced driver safety aids like airbags or electronic stability control systems beyond the luxury cars in which they first appeared. In this case, the auto industry has gotten ahead of possible NHTSA regulation and looks set to implement AEB itself. Speaking at an event last Fall , NHTSA Administrator Mark Rosekind said that NHTSA wanted to see OEMs implement AEB as quickly as possible. “Safety,” he said, “should not be a luxury item. Its an obligation for all of us.” Whether 2022 qualifies as “quickly” may be a matter of opinion, but may be reasonable given the long product development lifecycles of new vehicles. Read 1 remaining paragraphs | Comments

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10 more OEMs pledge to make auto-braking standard in new cars

Off-switch for overeating and obesity found in the brain

Littermates were injected with either a control virus (right) or a virus that knocked out O-GlcNAcTransferase (OGT) (left) in a subpopulation of cells in the hypothalamus in the brain. OGT knock out made the mouse eat twice as much as its sibling. This photo was taken about five weeks after virus injection. (credit: Olof Lagerlof ) After tediously tracking calories and willfully shunning cravings, many a dieter has likely dreamt of simple switch that, when thrown, could shut down hunger and melt away pounds—and scientists may have just found it. When researchers knocked down a single enzyme in the brains of mice, the rodents seemed to lose the ability to tell when they were full. They ate more than twice their usual amount of food at meal times and tripled their body fat within three weeks. And—most strikingly—when the researchers reversed the experiment, the mice just quickly stopped eating so much . Data on the enzymatic switch, published Thursday in Science , suggests a possible target for future drugs to treat obesity in humans. The enzyme is O-GlcNAc transferase, or OGT, which is known to work in a chemical pathway controlled by nutrients and metabolic hormones, particularly insulin. That pathway has long been linked with obesity. But researchers knew almost nothing about the how the pathway linked to the metabolic disorder or OGT’s specific role. Read 7 remaining paragraphs | Comments

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Off-switch for overeating and obesity found in the brain