Squid ink could make your dentist visits much less painful

Your dentist visits could become a pleasant pain-free experience, and it’s all thanks to squids . A team of engineers from the University of California San Diego have developed an imaging method using squid ink and ultrasound to check for gum disease. If you’ve ever had to get your mouth checked for gum issues, you know what I’m talking about: the current method to assess gum health involves inserting a periodontal probe’s metal hook in between your gums and teeth. Sometimes, depending on the dentist’s technique your pain tolerance, it hurts. The team’s method eliminates the need for probing — you simply need to gargle some food-grade squid ink mixed with water and cornstarch. Squid ink is rich in melanin nanoparticles, and those get trapped in the pockets between your teeth and gums. When a dentist shines a laser onto your mouth, the nanoparticles swell and create pressure differences in the gum pockets. That’s where the ultrasound part of the imaging method comes in. Ultrasound can detect those pockets, so dentists can create a full map of your mouth, like this: [Image credit: Jokerst Bioimaging Lab at UC San Diego. Ultrasound image of the teeth is in black and white. The photoacoustic signal from the squid ink contrast agent in the pocket depth is in red and signals from stains on the teeth are in blue. ] The result shows how deep those pockets are, which indicate gum health. That’s why dentists stick a probe in those pockets to begin with — if they’re only one to two millimeters in depth, it means your gums are healthy. Anything deeper than that is a sign of gum disease, and the deeper those pockets are, the worse the issue is. Problem is, the results of periodontal probing depend on the amount of pressure a dentist uses and the area he’s probing. He could be probing the wrong location or putting too little or too much pressure. Jesse Jokerst, the study’s senior author likened the periodontal probe to “examining a dark room with just a flashlight” wherein “you can only see one area at a time.” He said that their method is more like “flipping on all the light switches so you can see the entire room all at once, ” leading to more accurate findings. The engineers have big plans for their creation, starting with replacing the lasers in the method with more affordable LED lights. Their ultimate goal, however, is to create a mouthpiece that can instantly assess your gum health. They also want to get rid of the the squid ink concoction’s salty and bitter taste, though I’ll take than any day over painful probing. Source: UC San Diego

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Squid ink could make your dentist visits much less painful

Surgical robot makes highly precise eye injection possible

For the first time ever, a team of eye surgeons were able to inject a thrombolytic drug directly into a patient’s retinal vein to dissolve a blood clot. It was a success despite the fact that the vein is as thin as human hair thanks to a surgical robot developed by researchers from KU Leuven , a university in Belgium. The condition they treated is called retinal vein occlusion, and it leads to reduced eyesight and blindness. At the moment, doctors can only suppress its effects with monthly eye injections, because the retinal vein itself is only around 0.1 millimeter wide. It’s just much too thin for manual injections when the drug has to be administered for 10 minutes straight. Professor Peter Stalmans, an eye surgeon at University Hospitals Leuven, said: “The current treatment for retinal vein occlusion costs society €32.000 per eye. This is a high price tag, considering that you’re only treating the side effects and that there is little more you can do than avoid reducing eyesight. The robotic device finally enables us to treat the cause of the thrombosis in the retina. I look forward to what is next: if we succeed, we will literally be able to make blind people see again.” To address the issue, the researchers created a robot that can help a surgeon insert the needle precisely and then hold it perfectly still. They also designed the 0.03 millimeter needle, which is three times thinner than human hair, needed to inject the drug into the tiny vein. According to the university, the method successfully dissolved the blood clot and the patient is now doing well. However, it’ll take some time before everyone else who has the condition can go through the same treatment: the surgery was merely part of the first phase of the method’s clinical trial. The surgeons have to replicate the procedure’s success on other patients and then study its effects in the trial’s second phase. Source: KU Leuven

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Surgical robot makes highly precise eye injection possible