75-year-old human cloned for the production of stem cells

sharyn morrow Several years ago, as the therapeutic potential of stem cells was first being recognized, the only way to create them was to harvest cells from an early embryo. That embryo could come from the large collection of those that weren’t used during in vitro fertilization work. But to get one that was genetically matched to the person who needed the therapy, researchers had to create an embryo that’s a genetic duplicate of that individual—meaning they had to clone them. With the development of induced stem cells, work on this approach largely fell by the wayside—induced cells were easier to create and came without the ethical baggage. But there are some lingering doubts that the induced cells are truly as flexible as the ones derived from an embryo, leading a number of labs to continue exploring cloning for therapeutic purposes. Now, a collaboration of US and Korean researchers have succeeded in creating early embryos from two adult humans and converted the embryos to embryonic stem cells. The method used is called somatic cell nuclear transplant. It involves taking an unfertilized egg and removing its nucleus, thereby deleting the DNA of the egg donor. At the same time, a nucleus from the cell of a donor is carefully removed and injected into the egg. After some time, during which the environment of the egg resets the developmental status of the donor’s DNA, cell division is activated. If the process is successful, the end result is a small cluster of cells that starts along the path of forming an embryo. Read 5 remaining paragraphs | Comments

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75-year-old human cloned for the production of stem cells

After Netflix pays Comcast, speeds improve 65%

Netflix’s decision to pay Comcast for a direct connection to the Comcast network has resulted in significantly better video streaming performance for customers of the nation’s largest broadband provider. Netflix has bemoaned the payment, asking the government to prevent Comcast from demanding such interconnection ” tolls .”But there’s little doubt the interconnection has benefited consumers in the short term. Average Netflix performance for Comcast subscribers rose from 1.51Mbps to 1.68Mbps from January to February, though the interconnection didn’t begin until late February. In data released today, Netflix said average performance on Comcast has now risen further  to 2.5Mbps , a 65 percent increase since January. Comcast’s increased speed allowed it to pass Time Warner Cable, Verizon, CenturyLink, AT&T U-verse, and others in Netflix’s rankings. Comcast remains slower than Cablevision, Cox, Suddenlink, Charter, and Google Fiber. Read 4 remaining paragraphs | Comments

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After Netflix pays Comcast, speeds improve 65%

Flowing salt water over graphene generates electricity

An image of graphene, showing defects in its single-atom thickness. UC Berkeley Hydroelectricity is one of the oldest techniques for generating electrical power, with over 150 countries using it as a source for renewable energy. Hydroelectric generators only work efficiently at large scales, though—scales large enough to interrupt river flow and possibly harm local ecosystems. And getting this sort of generation down to where it can power small devices isn’t realistic. In recent years, scientists have investigated generating electrical power using nano-structures. In particular, they have looked at generating electricity when ionic fluids—a liquid with charged ions in it—are pushed through a system with a pressure gradient. However, the ability to harvest the generated electricity has been limited because it requires a pressure gradient to drive ionic fluid through a small tube. But scientists have now found that dragging small droplets of salt water on strips of graphene generates electricity without the need for pressure gradients. In their study, published in Nature Nanotechnology , researchers from China grew a layer of graphene and placed a droplet of salt water on it. They then dragged the droplet across the graphene layer at different velocities and found that the process generated a small voltage difference. Read 6 remaining paragraphs | Comments

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Flowing salt water over graphene generates electricity

Appeals court reverses hacker/troll “weev” conviction and sentence [Updated]

Self-portrait by Weev A federal appeals court Friday reversed and vacated the conviction and sentence of hacker and Internet troll Andrew “weev” Auernheimer. The case against Auernheimer, who has often been in solitary confinement for obtaining and disclosing personal data of about 140,000 iPad owners from a publicly available AT&T website, was seen as a test case on how far the authorities could go under the Computer Fraud and Abuse Act, the same law that federal prosecutors were invoking against Aaron Swartz. But, in the end, the Third U.S. Circuit Court of Appeals didn’t squarely address the controversial fraud law and instead said Aeurnheimer was charged in the wrong federal court. Read 4 remaining paragraphs | Comments

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Appeals court reverses hacker/troll “weev” conviction and sentence [Updated]

Whitehat hacker goes too far, gets raided by FBI, tells all

A whitehat hacker from the Baltimore suburbs went too far in his effort to drive home a point about a security vulnerability he reported to a client. Now he’s unemployed and telling all on reddit . David Helkowski was working for Canton Group, a Baltimore-based software consulting firm on a project for the University of Maryland (UMD), when he claims he found malware on the university’s servers that could be used to gain access to personal data of students and faculty. But he says his employer and the university failed to take action on the report, and the vulnerability remained in place even after a data breach exposed more than 300,000 students’ and former students’ Social Security numbers. As Helkowski said to a co-worker in Steam chat, “I got tired of being ignored, so I forced their hand.” He penetrated the university’s network from home, working over multiple VPNs, and downloaded the personal data of members of the university’s security task force. He then posted the data to Pastebin and e-mailed the members of the task force anonymously on March 15. Read 6 remaining paragraphs | Comments

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DNA-based logic gates operate inside cockroach cells

DNA robots crawl across a surface made of DNA. Harvard DNA-based nanotechnology has been around for more than 30 years, but it really took off in 2006, when DNA origami was featured on the cover of Nature . This form of origami, the folding of DNA into 2D and 3D shapes, was more of an art form back then, but scientists are now using the approach to construct nanoscale robots. The basic principle of DNA origami is that a long, single-stranded DNA molecule will fold into a predefined shape through the base-pairing of short segments called staples. All that’s required is to ensure that each staple can find a complementary match to base-pair with at the right location elsewhere in the molecule. This approach can be used to create both 2D and 3D structures. The idea behind the new work is that a DNA origami robot can be programmed to have a specific function based on a key, which can be a protein, a drug, or even another robot. Once the right key and the right robot find each other, the key drives a conformational (structural) change in the robot. The new shape causes the robot to perform a programmed function, such as releasing a drug. Read 7 remaining paragraphs | Comments

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DNA-based logic gates operate inside cockroach cells

Heartbleed vulnerability may have been exploited months before patch

guthrieinator There’s good news, bad news, and worse news regarding the “Heartbleed” bug that affected nearly two-thirds of the Internet’s servers dependent on SSL encryption. The good news is that many of those servers (well, about a third) have already been patched. And according to analysis by Robert Graham of Errata Security, the bug won’t expose the private encryption key for servers “in most software” (though others have said several web server distributions are vulnerable to giving up the key under certain circumstances.) The bad news is that about 600,000 servers are still vulnerable to attacks exploiting the bug. The worse news is that malicious “bot” software may have been attacking servers with the vulnerability for some time—in at least one case, traces of the attack have been found in audit logs dating back to last November. Attacks based on the exploit could date back even further. Security expert Bruce Schneier calls  Heartbleed  a catastrophic vulnerability. “On the scale of 1 to 10, this is an 11,” he said in a  blog post today.  The bug affects how OpenSSL, the most widely used cryptographic library for Apache and nginx Web servers, handles a service of Transport Layer Security called Heartbeat—an extension added to TLS in 2012. Read 9 remaining paragraphs | Comments

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Heartbleed vulnerability may have been exploited months before patch

Critical crypto bug exposes Yahoo Mail passwords Russian roulette-style

Mascamon at lb.wikipedia Lest readers think “catastrophic” is too exaggerated a description for the critical defect affecting an estimated two-thirds of the Internet’s Web servers , consider this: at the moment this article was being prepared, the so-called Heartbleed bug was exposing end-user passwords, the contents of confidential e-mails, and other sensitive data belonging to Yahoo Mail and almost certainly countless other services. The two-year-old bug is the result of a mundane coding error in OpenSSL , the world’s most popular code library for implementing HTTPS encryption in websites, e-mail servers, and applications. The result of a missing bounds check in the source code, Heartbleed allows attackers to recover large chunks of private computer memory that handle OpenSSL processes. The leak is the digital equivalent of a grab bag that hackers can blindly reach into over and over simply by sending a series of commands to vulnerable servers. The returned contents could include something as banal as a time stamp, or it could return far more valuable assets such as authentication credentials or even the private key at the heart of a website’s entire cryptographic certificate. Underscoring the urgency of the problem, a conservatively estimated two-thirds of the Internet’s Web servers use OpenSSL to cryptographically prove their legitimacy and to protect passwords and other sensitive data from eavesdropping. Many more e-mail servers and end-user computers rely on OpenSSL to encrypt passwords, e-mail, instant messages, and other sensitive data. OpenSSL developers have released version 1.0.1g that readers should install immediately on any vulnerable machines they maintain. But given the stakes and the time it takes to update millions of servers, the risks remain high. Read 6 remaining paragraphs | Comments

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Critical crypto bug exposes Yahoo Mail passwords Russian roulette-style

Intel expands 10Gbps “Thunderbolt Ethernet” capability to Windows

Thunderbolt 2 is picking up another feature. Chris Foresman If standard gigabit Ethernet isn’t cutting it for you, Intel will soon give you another option: this week at the National Association of Broadcasters (NAB) show in Las Vegas, the company announced a new feature called ” Thunderbolt Networking ” that will soon be available to all PCs with Thunderbolt 2 controllers. The feature, which will be enabled by an upcoming Windows driver update, will “emulat[e] an Ethernet connection environment” and provide a 10Gbps two-way link between two computers connected with a Thunderbolt cable. Since you’ll need to connect the two computers directly to each other, this solution obviously won’t scale as well as real 10Gbps networking equipment. But for now, that hardware remains relatively uncommon and expensive—well outside the price range of individuals and smaller businesses. Thunderbolt Networking is apparently not being enabled for older computers with first-generation Thunderbolt controllers. While the feature will be new to the Windows operating system, the ability to network two Thunderbolt Macs together was introduced back in Mavericks. It doesn’t appear to require Thunderbolt 2 on that platform, though as we experienced , configuring a Thunderbolt Bridge can make for fast but occasionally choppy transfer speeds. That test connected one Thunderbolt 2 Mac to an older model with a first-generation Thunderbolt controller, though—it’s possible that connecting Thunderbolt 2 Macs to each other results in a more stable connection however. This new Windows driver update will enable any two Thunderbolt 2 PCs and Macs to be connected, though to date the Windows laptops, workstations, and motherboards with integrated Thunderbolt 2 controllers have been few and far between. Read on Ars Technica | Comments

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Intel expands 10Gbps “Thunderbolt Ethernet” capability to Windows

Microsoft looking into Xbox 360 emulation through Xbox One

Mark Derricutt When the Xbox One was announced last year, many Xbox 360 owners were upset that the system wouldn’t be backward compatible with 360 games . Now, there’s some indication that Microsoft is looking to remedy this situation through emulation, though the specific timing or form that the emulation will take is still unclear. Microsoft’s still-nebulous plans for Xbox 360 emulation via the Xbox One come from a Q&A session at last week’s Build developers conference , as reported by Kotaku AU . When an audience member asked if there were “plans for an Xbox 360 emulator on Xbox One,” Microsoft Partner Development Lead Frank Savage responded: There are, but we’re not done thinking them through yet, unfortunately. It turns out to be hard to emulate the PowerPC stuff on the X86 stuff. So there’s nothing to announce, but I would love to see it myself. The change in architecture between the Xbox 360’s PowerPC processor and Xbox One’s x86 chip has  long been  suspected as the main reason that the newer system can’t natively play games from its predecessor. The PS4 saw a similar architecture change from the PS3 and also lacks native backward compatibility. Read 2 remaining paragraphs | Comments

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Microsoft looking into Xbox 360 emulation through Xbox One