Scientists Use Stem Cells To Grow Animal-Free Pork In a Lab

A new study published in the journal Scientific Reports describes research “designed to generate muscle from a newly established pig stem-cell line, rather than from primary cells taken directly from a pig, ” says co-author Dr. Nicholas Genovese, a stem-cell biologist. “This entailed understanding the biology of relatively uncharacterized and recently-derived porcine induced pluripotent stem cell lines. What conditions support cell growth, survival and differentiation? These are all questions I had to figure out in the lab before the cells could be turned into muscle.” Digital Trends reports: It may not sound like the most appetizing of foodstuffs, but pig skeletal muscle is in fact the main component of pork. The fact that it could be grown from a stem-cell line, rather than from a whole pig, is a major advance. This is also true of the paper’s second big development: the fact that this cultivation of pig skeletal muscle didn’t use animal serum, a component which has been used in other livestock muscle cultivation processes. [Genovese] acknowledges that there are other non-food-related possibilities the work hints at. “There is a contingent interest in using the pig as a model to study disease and test regenerative therapies for human conditions, ” he said. Read more of this story at Slashdot.

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Scientists Use Stem Cells To Grow Animal-Free Pork In a Lab

Fewer People Are Dying of Cancer Than Ever Before

The number of Americans dying of cancer has dropped to a 25-year low, equaling an estimated 2, 143, 200 fewer deaths in that period, says the new annual report from the American Cancer Society. In that time, the racial and gender disparities that exist in cancer rates have also narrowed somewhat, but they remain wide in many places. From a report on The Outline: Though the incidence of cancer remained stable for women and dropped slightly — by 2 percent — in men, rates remain overall 20 percent higher in men while rate of death for men is 40 percent higher than in women. The rates of both incidence and death vary wildly based on the type of cancer. The data that the ACS is using run through the end of 2014 for incidents of cancer and through 2013 for deaths. Lung cancer remains the leading cause of cancer death in the United States for both men and women.. Read more of this story at Slashdot.

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Fewer People Are Dying of Cancer Than Ever Before

China Claims Tests of ‘Reactionless’ EM Drive Were Successful

An anonymous reader quotes a report from Popular Science: The “reactionless” Electromagnetic Drive, or EmDrive for short, is an engine propelled solely by electromagnetic radiation confined in a microwave cavity. Such an engine would violate the law of conservation of momentum by generating mechanical action without exchanging matter. But since 2010, both the United States and China have been pouring serious resources into these seemingly impossible engines. And now China claims its made a key breakthrough. Dr. Chen Yue, Director of Commercial Satellite Technology for the China Academy of Space Technology (CAST) announced on December 10, 2016 that not only has China successfully tested EmDrives technology in its laboratories, but that a proof-of-concept is currently undergoing zero-g testing in orbit (according to the International Business Times, this test is taking place on the Tiangong 2 space station). If China is able to install EmDrives on its satellites for orbital maneuvering and altitude control, they would become cheaper and longer lasting. Li Feng, lead CAST designer for commercial satellites, states that the current EmDrive has only a thrust of single digit millinewtons, for orbital adjustment; a medium sized satellite needs 0.1-1 Newtons. A functional EmDrive would also open up new possibilities for long range Chinese interplanetary probes beyond the Asteroid belt, as well freeing up the mass taken up by fuel in manned spacecraft for other supplies and equipment to build lunar and Martian bases. On the military side of things, EmDrives could also be used to create stealthier, longer lasting Chinese surveillance satellites. Read more of this story at Slashdot.

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China Claims Tests of ‘Reactionless’ EM Drive Were Successful

China Chokes On Smog So Bad That Planes Can’t Land

Major cities across northern China choked Monday under a blanket of smog so thick that industries were ordered shut down and air and ground traffic was disrupted. From a report: At least 23 cities issued red alerts for a swath of pollution that has hovered over much of the nation since Friday, China’s Xinhua news agency reported. Alerts are expected to remain in effect through Wednesday. Hospitals set emergency procedures in motion to deal with an influx of breathing-related illnesses. Large hospitals in the port city of Tianjin, less than 100 miles southeast of Beijing, saw a surge in asthma and other respiratory issues, China’s People’s Daily reported. The pollution forced the city to close the highways and caused delays and cancellations for dozens of flights, Xinhua said. Read more of this story at Slashdot.

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China Chokes On Smog So Bad That Planes Can’t Land

Cesarean Births Could Be Affecting Human Evolution, Study Says

CanadianRealist writes: Larger babies delivered by cesarean section may be affecting human evolution. Researchers estimate cases where the baby cannot fit down the birth canal have increased from 30 in 1, 000 in the 1960s to 36 in 1, 000 births today, [according to estimates from researchers at the University of Vienna in Austria.] Science Alert reports: “In the past, larger babies and mothers with narrow pelvis sizes might both have died in labour. Thanks to C-sections, that’s now a lot less likely, but it also means that those ‘at risk’ genes from mothers with narrow pelvises are being carried into future generations. More detailed studies would be required to actually confirm the link between C-sections and evolution, as all we have now is a hypothesis based on the birth data.” Agreed, more studies required part. Cesareans may simply be becoming more common with “too large” defined as cesarean seems like a better idea. It’s reasonable to pose the question based simply on an understanding of evolution. Like it’s reasonable to conjecture that length of human pregnancy is a compromise between further development in utero, and chance of mother and baby surviving the delivery. Read more of this story at Slashdot.

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Cesarean Births Could Be Affecting Human Evolution, Study Says

Scientists Discover Antibody That Neutralizes 98% of HIV Strains

An anonymous reader quotes a report from The Inquisitr: The National Institute of Allergy and Infectious Diseases (NIAID) announced this week that a “remarkable” breakthrough has been made in the study of preventing and treating the human immunodeficiency virus (HIV), the virus that leads to acquired immunodeficiency syndrome (AIDS), according to a press release posted on the agency’s official website. The breakthrough centers around the discovery of a powerful antibody named N6 that is highly effective in both binding to the surface of the HIV virus and neutralizing it. The former has proved elusive in the past. “Identifying broadly neutralizing antibodies against HIV has been difficult because the virus rapidly changes its surface proteins to evade recognition by the immune system, ” the press release explains. The antibody was initially discovered in an HIV-positive person and has since proven to potentially neutralize 98 percent of HIV isolates, “including 16 of 20 strains resistant to other antibodies of the same class, ” according to the press release. Researchers have had previous success with other antibodies, but N6 appears to be more effective. The new discovery has potential benefits far beyond preventing and treating HIV as well. Studying exactly how N6 works could potentially lead to breakthroughs in other anti-viral antibodies. “Findings from the current study showed that N6 evolved a unique mode of binding that depends less on a variable area of the HIV envelope known as the V5 region and focuses more on conserved regions, which change relatively little among HIV strains, ” NIAID explains. “This allows N6 to tolerate changes in the HIV envelope, including the attachment of sugars in the V5 region, a major mechanism by which HIV develops resistance to other VRC01-class antibodies. Due to its potency, N6 may offer stronger and more durable prevention and treatment benefits, and researchers may be able to administer it subcutaneously (into the fat under the skin) rather than intravenously. In addition, its ability to neutralize nearly all HIV strains would be advantageous for both prevention and treatment strategies.” Read more of this story at Slashdot.

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Scientists Discover Antibody That Neutralizes 98% of HIV Strains

First Color Images Produced By an Electron Microscope

Slashdot reader sciencehabit quotes Science magazine: Imagine spending your whole life seeing the world in black and white, and then seeing a vase of roses in full color for the first time. That’s kind of what it was like for the scientists who have taken the first multicolor images of cells using an electron microscope. Electron microscopes can magnify an object up to 10 million times, allowing researchers to peer into the inner workings of, say, a cell or a fly’s eye, but until now they’ve only been able to see in black and white. The new advance — 15 years in the making — uses three different kinds of rare earth metals called lanthanides…layered one-by-one over cells on a microscope slide. The microscope detects when each metal loses electrons and records each unique loss as an artificial color. Read more of this story at Slashdot.

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First Color Images Produced By an Electron Microscope

Every Year of Smoking Causes About 150 New DNA Mutations That Can Make Cancer More Likely, Says Study

An anonymous reader quotes a report from Los Angeles Times: For every year that you continue your pack-a-day habit, the DNA in every cell in your lungs acquires about 150 new mutations. Some of those mutations may be harmless, but the more there are, the greater the risk that one or more of them will wind up causing cancer. The threat doesn’t stop there, according to a study in Friday’s edition of the journal Science. After a year of smoking a pack of cigarettes each day, the cells in the larynx pick up roughly 97 new mutations, those in the pharynx accumulate 39 new mutations, and cells in the oral cavity gain 23 new mutations. Even organs with no direct exposure to tobacco smoke appear to be affected. The researchers counted about 18 new mutations in every bladder cell and six new mutations in every liver cell for each “pack-year” that smokers smoked. The findings are based on a genetic analysis of 5, 243 cancers, including 2, 490 from smokers and 1, 063 from patients who said they had never smoked tobacco cigarettes. The researchers used powerful supercomputers to compare thousands of cancer genome sequences. The computers grouped the sequences into about 20 distinct categories, or “mutational signatures.” Mutations tied to five of these signatures were more common in tumors from smokers than in tumors from nonsmokers. One of the signatures involves a specific DNA nucleobase change — instead of a C for cytosine, there was an A for adenine — that “is very similar” to the change that occurs in the lab when cells are exposed to benzo[a]pyrene, a compound that the International Agency for Research on Cancer says is carcinogenic to humans. Most of the lung and larynx cancers obtained from smokers had this type of mutation, the researchers reported. They also found that the signature was more common among smokers than nonsmokers. Another mutational signature was characterized by Cs that should have been Ts (thymine) and vice versa. Although these changes can be found in all kinds of cancers, the signature was 1.3 to 5.1 times more common in tumors from smokers than in tumors from nonsmokers, according to the study. Read more of this story at Slashdot.

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Every Year of Smoking Causes About 150 New DNA Mutations That Can Make Cancer More Likely, Says Study

MuckRock Identifies The Oldest US Government Computer Still in Use

Slashdot reader v3rgEz writes: When MuckRock started using public records to find the oldest computer in use by the U.S. government, they scoured the country — but it wasn’t until a few tipsters that they set their sights a little higher and found that the oldest computer in use by the government might be among other planets entirely. The oldest computer still in use by the U.S. government appears to be the on-board systems for the Voyager 1 and 2 space probes — nearly 40 years old, and 12.47 billion miles away from earth. (Last year NASA put out a call for a FORTRAN programmer to upgrade the probes’ software.) But an earlier MuckRock article identified their oldest software still in use on earth — “the computers inside the IRS that makes sure everybody is paying their taxes”. And it also identified their oldest hardware still in use — “the machines running the nuclear defense system”. (The launch commands are still stored on 8-inch floppy disks.) Read more of this story at Slashdot.

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MuckRock Identifies The Oldest US Government Computer Still in Use

Microsoft Edge Is the Official Name of the IE-Slaying Spartan Browser

One of the most exciting additions to Microsoft’s upcoming Windows 10 operating system is the IE browser killer, Project Spartan. We’ve been excited for months and months, but Spartan was never even meant to be the new browser’s final name, but today Microsoft revealed the official moniker of its next-gen window to the internet—Microsoft Edge! Read more…

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Microsoft Edge Is the Official Name of the IE-Slaying Spartan Browser