FDA Declares Popular Alt-Medicine Kratom an Opioid

An anonymous reader quotes a report from NBC News: The Food and Drug Administration declared the popular herbal product kratom to be an opioid on Tuesday, opening a new front in its battle to get people to stop using it. New research shows kratom acts in the brain just as opioids do, FDA Commissioner Dr. Scott Gottlieb said in a statement. And he said the agency has documented 44 cases in which kratom at least helped kill people — often otherwise healthy young people. “Taken in total, the scientific evidence we’ve evaluated about kratom provides a clear picture of the biologic effect of this substance, ” Gottlieb wrote. “Kratom should not be used to treat medical conditions, nor should it be used as an alternative to prescription opioids. There is no evidence to indicate that kratom is safe or effective for any medical use.” The FDA released detailed accounts of several of the deaths. The victims often had mixed kratom with other substances, including chemicals taken out of inhalers and found in over-the-counter cold and flu drugs. Read more of this story at Slashdot.

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FDA Declares Popular Alt-Medicine Kratom an Opioid

Foxconn Unit To Cut Over 10,000 Jobs As Robotics Take Over

According to Nikkei Asian Review, “Foxconn’s panel arm Innolux is planning to slash more than 10, 000 jobs this year as part of the company’s aggressive efforts to increase the use of automation in manufacturing.” Honorary Chairman Tuan Hsing-Chien said in a press conference on Tuesday: “We will reduce our total workforce to less than 50, 000 people by the end of this year, from some 60, 000 staff at the end of 2017.” From the report: Innolux is a liquid crystal display-making affiliate of major iPhone assembler Hon Hai Precision Industry, better known as Foxconn Technology Group. Tuan is also a technology adviser to Foxconn, Sharp and Innolux. Tuan said up to 75% of production will be fully automated by the end of 2018. Most of Innolux’s factories are in Taiwan. Tuan’s pledge came a few days after Foxconn Chairman Terry Gou said the company would pour in some $342 million to overhaul its manufacturing process by using artificial intelligence. Read more of this story at Slashdot.

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Foxconn Unit To Cut Over 10,000 Jobs As Robotics Take Over

Samsung Made a Bitcoin Mining Rig Out of 40 Old Galaxy S5s

An anonymous reader quotes a report from Motherboard: Samsung is starting a new “Upcycling” initiative that is designed to turn old smartphones and turn them into something brand new. Behold, for example, this bitcoin mining rig, made out of 40 old Galaxy S5 devices, which runs on a new operating system Samsung has developed for its upcycling initiative. Samsung premiered this rig, and a bunch of other cool uses for old phones, at its recent developer’s conference in San Francisco. Upcycling involves repurposing old devices instead of breaking them down for parts of reselling them. The people at Samsung’s C-Lab — an engineering team dedicated to creative projects — showed off old Galaxy phones and assorted tablets stripped of Android software and repurposed into a variety of different objects. The team hooked 40 old Galaxy S5’s together to make a bitcoin mining rig, repurposed an old Galaxy tablet into a ubuntu-powered laptop, used a Galaxy S3 to monitor a fishtank, and programed an old phone with facial recognition software to guard the entrance of a house in the form of an owl. Samsung declined to answer specific questions about the bitcoin mining rig, but an information sheet at the developer’s conference noted that eight galaxy S5 devices can mine at a greater power efficiency than a standard desktop computer (not that too many people are mining bitcoin on their desktops these days). Read more of this story at Slashdot.

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Samsung Made a Bitcoin Mining Rig Out of 40 Old Galaxy S5s

US scientists have genetically modified human embryos

A team of scientists from Oregon have performed the first known instance of gene editing on human embryos in the US, according to MIT’s Tech Review . Shoukhrat Mitalipov from Oregon Health and Science University and his team have reportedly corrected defective genes that cause inherited diseases in “a large number of one-cell embryos” using CRISPR . Mitalipov refused to comment on the results of the project, but some of his collaborators already confirmed them to the publication. Up until now, reports about human-related gene editing usually come from outside the US. China, in particular, hasn’t been holding back when it comes to CRISPR experimentation. Scientists from the country were the first to use the technique on human embryos to repair a gene that causes fatal blood disorder. A team of oncologists from Sichuan University also conducted the first CRISPR human trial on a patient suffering from an aggressive form of lung cancer. In the US, Congress blocked clinical trials that involve genetically modifying human embryos. The practice raises a lot of ethical concerns, after all, with critics being especially worried that it could lead to designer babies. The National Academy of Sciences issued a report in early 2017 endorsing human germline modification, though, and that’s exactly what Mitalipov’s group did. Modifying an embryo to eradicate heritable diseases is called “germline engineering, ” because the child born from that embryo will pass on the changes with his or her germ (egg or sperm) cells. We won’t find out if that’s true with Mitalipov’s study, because it was never meant to be a clinical trial. The team didn’t allow the embryos to develop for more than a couple of days, and they were never meant to be implanted into a womb. What we’ve found out, however, is that it’s possible to use CRISPR to edit embryos without causing an error called “mosaicism.” In previous attempts by Chinese scientists, CRISPR caused an editing error wherein the DNA changes they made were only taken up by some, not all, of the cells the embryos developed. The Oregon group managed to avoid that problem by injecting CRISPR segments — DNA segments used to cut out unwanted genes — and sperm cells into the eggs at the same time. It’s unclear what illnesses were involved exactly, but they used sperm donated by subjects with various inheritable diseases. One of the scientists familiar with the study told Tech Review : “It is proof of principle that it can work. They significantly reduced mosaicism. I don’t think it’s the start of clinical trials yet, but it does take it further than anyone has before.” The team’s results are still pending publication, so we’ll likely hear more details about the study in the future. Source: MIT Technology Review

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US scientists have genetically modified human embryos

A fascinating graphic novel about the origins of Dungeons & Dragons

Almost 10 years ago, journalist David Kushner had a chance to interview Gary Gygax and Dave Arneson, the two creators of Dungeons & Dragons , before they died. Kushner’s reporting became a story for Wired , and now he’s expanded the scope of his tale into a graphic novel. Rise of the Dungeon Master , beautifully illustrated by Koren Shadmi, is both a moving portrait of two creative outsiders and a chronicle of how a new kind of storytelling changed pop culture forever. Kushner recounts the story of Gygax and Arneson in the second person, addressing the reader as if Kushner were the dungeon master. “You” are young Gygax, the child of immigrants growing up in the midwest, seeking escape from ordinary life by exploring the wilderness, hunting, and eventually learning to break into an old, abandoned asylum. The narrative technique sounds gimmicky, but it works: you’re sucked into the story and into immediate sympathy with Gygax as he traces his fascination with adventure games back to his childhood, when he climbed around in the maze of tunnels below the creepy asylum’s rotting rooms. Nation Books Read 7 remaining paragraphs | Comments

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A fascinating graphic novel about the origins of Dungeons & Dragons

Female Shark Learns To Reproduce Without Males After Years Alone

An anonymous reader quotes a report from New Scientist: A female shark separated from her long-term mate has developed the ability to have babies on her own. Leonie the zebra shark (Stegostoma fasciatum) met her male partner at an aquarium in Townsville, Australia, in 1999. They had more than two dozen offspring together before he was moved to another tank in 2012. From then on, Leonie did not have any male contact. But in early 2016, she had three baby sharks. Intrigued, Christine Dudgeon at the University of Queensland in Brisbane, Australia, and her colleagues began fishing for answers. One possibility was that Leonie had been storing sperm from her ex and using it to fertilize her eggs. But genetic testing showed that the babies only carried DNA from their mum, indicating they had been conceived via asexual reproduction. Some vertebrate species have the ability to reproduce asexually even though they normally reproduce sexually. These include certain sharks, turkeys, Komodo dragons, snakes and rays. However, most reports have been in females who have never had male partners. In sharks, asexual reproduction can occur when a female’s egg is fertilized by an adjacent cell known as a polar body, Dudgeon says. This also contains the female’s genetic material, leading to “extreme inbreeding”, she says. “It’s not a strategy for surviving many generations because it reduces genetic diversity and adaptability.” Nevertheless, it may be necessary at times when males are scarce. “It might be a holding-on mechanism, ” Dudgeon says. “Mum’s genes get passed down from female to female until there are males available to mate with.” It’s possible that the switch from sexual to asexual reproduction is not that unusual; we just haven’t known to look for it, Dudgeon says. Read more of this story at Slashdot.

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Female Shark Learns To Reproduce Without Males After Years Alone

Pregnancy Alters Woman’s Brains ‘For At Least Two Years’

EzInKy writes: The BBC and others are reporting the results of a study that women’s brains do in fact change during pregnancy. BBC reports: “Pregnancy reduces grey matter in specific parts of a woman’s brain, helping her bond with her baby and prepare for the demands of motherhood. Scans of 25 first-time mums showed these structural brain changes lasted for at least two years after giving birth. European researchers said the scale of brain changes during pregnancy were akin to those seen during adolescence. But they found no evidence of women’s memory deteriorating. This study, from researchers at the Universitat Autonoma de Barcelona and Leiden University and published in Nature Neuroscience, looked at the brain scans of women before they became pregnant, soon after they gave birth, and two years later, to see how the brain changed. And they compared these women’s brains with those of 19 first-time fathers, 17 men without children and 20 women who had never given birth. The researchers found ‘substantial’ reductions in the volume of grey matter in the brains of first-time mothers. The grey matter changes occurred in areas of the brain involved in social interactions used for attributing thoughts and feelings to other people — known as ‘theory-of-mind’ tasks. The researchers thought this would give new mothers an advantage in various ways – help them recognize the needs of their child, be more aware of potential social threats and become more attached to their baby.” Thanks Mom! As for first-time fathers, the researchers found no changes in their grey matter. Read more of this story at Slashdot.

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Pregnancy Alters Woman’s Brains ‘For At Least Two Years’

You Can Soon Buy That Tiny Scooter That Looks Like a Laptop You Can Ride

A Segway you can carry in a laptop bag? That’s what Cocoa Motors promised when it revealed the WalkCar , an ultra-compact personal transport, last year. And finally, after a year of perfecting its design, the WalkCar will be available for pre-order starting on October 21. Read more…

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You Can Soon Buy That Tiny Scooter That Looks Like a Laptop You Can Ride

Facebook’s Bad Year Just Got a Lot Worse

While Facebook’s stock has continued to boom throughout 2016, this year has been full of PR nightmares for the world’s most popular social network, which, among other things, has been accused of censorship , grilled by the US Senate and sued by the IRS in recent months. On Thursday, however, that bad press finally became something that could hurt its bottom line when news broke that Facebook juiced a key stat to advertisers, inflating it by “60 to 80 percent” for years. Read more…

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Facebook’s Bad Year Just Got a Lot Worse

Anonymous Hacker Explains His Attack On Boston Children’s Hospital

Okian Warrior writes: Martin Gottesfeld of Anonymous was arrested in connection with the Spring 2014 attacks on a number of healthcare and treatment facilities in the Boston area. The attacks were in response/defense of a patient there named Justina Pelletier. Gottesfeld now explains why he did what he did, in a statement provided to The Huffington Post. Here’s an excerpt from his statement: [Why I Knocked Boston Children’s Hospital Off The Internet] The answer is simpler than you might think: The defense of an innocent, learning disabled, 15-year-old girl. In the criminal complaint, she’s called ‘Patient A, ‘ but to me, she has a name, Justina Pelletier. Boston Children’s Hospital disagreed with her diagnosis. They said her symptoms were psychological. They made misleading statement on an affidavit, went to court, and had Justina’s parents stripped of custody. They stopped her painkillers, leaving her in agony. They stopped her heart medication, leaving her tachycardic. They said she was a danger to herself, and locked her in a psych ward. They said her family was part of the problem, so they limited, monitored, and censored her contact with them…” Read more of this story at Slashdot.

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Anonymous Hacker Explains His Attack On Boston Children’s Hospital