Enlarge / Nanoparticles (black dots) sit in the remains of a cell they’ve helped kill. (credit: University of Michigan ) One of the ways to kill a cancer is to cook it, since heat can kill cells. The trick, of course, is to only cook the cancer and not the surrounding tissue. To do this, you need to have an accurate idea of the extent of a tumor, a precise mechanism for delivering heat, and a damn good thermometer. It may surprise you to learn that gold nanoparticles do a pretty good job of achieving the first two. The third—a good thermometer—has eluded researchers for quite some time. But, now it seems that gold nanoparticles may provide the full trifecta . Drowning a tumor in molten gold Some cancers—the ones most people imagine when they think of cancer—form lumps of tissue. At some point, these lumps require a blood supply. Once supplied with blood vessels, the tumor can not only grow, but it has a readily available transport system to deliver the cells that can spread the cancer throughout the body. For the patient, this is not good news. The development of a blood supply opens up new imaging and treatment options, though. Cancer tumors are not well-organized tissues compared to healthy tissue like muscle or kidney tissue. So there are lots of nooks and crannies in a tumor that can trap small particles. And this disorganization is exactly what researchers hope to take advantage of. Gold nanoparticles are injected into the blood stream; these exit the blood supply, but, in most of the body, they get rapidly cleaned out. Except that, inside tumors, the nanoparticles lodge all over the place. Read 22 remaining paragraphs | Comments
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How gold nanoparticles may make killing tumors easier
Cummins has beat Tesla to the punch by unveiling its own electric semi truck. According to Forbes, the fully electric, class 7 day-cab urban hauler, called Aeos, gets 100 miles of range from its 140-kWh battery pack and can haul a 22-ton trailer. While the company does offer the options of additional battery packs to triple the range or a range-extending engine generator, the Aeos is better suited for city use rather than long-haul trucking. Autoblog reports: While this electric truck is a concept, it’s a working demonstration of a product Cummins plans to start producing in 2019. At the unveiling in Columbus, Ind., Cummins also revealed its latest near-zero-emissions natural gas engines, as well as the X15 and lightweight X12 clean diesel engines. The company said it is embracing new technologies that allow its customers to contribute to a sustainable future. Read more of this story at Slashdot. 
HughPickens.com writes: For many drivers, the app Waze is a godsend, providing real-time, crowdsourced traffic tips to motorists desperate for alternatives to congested thoroughfares but to some residents of the formerly quiet neighborhoods through which Waze has rerouted countless commuters, the app has destroyed their quality of life. Steve Hendrix writes at the Washington Post that when traffic on Timothy Connor’s quiet Maryland street in Tamoka Park, MD suddenly jumped by several hundred cars an hour, he knew that Waze was to blame for routing cars around a months-long road repair through his neighborhood. “I could see them looking down at their phones, ” says Connor. “We had traffic jams, people were honking. It was pretty harrowing.” So Connor became a Waze Warrior. Every rush hour, he went on the Google-owned social-media app and posted false reports of a wreck, speed trap or other blockage on his street, hoping to deflect some of the flow. Neighbors filed false reports of blockages, sometimes with multiple users reporting the same issue to boost their credibility. “It used to be that only locals knew all the cut-through routes, but Google Maps and Waze are letting everyone know, ” says Bates Mattison. “In some extreme cases, we have to address it to preserve the sanctity of a residential neighborhood.” But Waze was way ahead of them. It’s not possible to fool the system for long, according to Waze officials. For one thing, the system knows if you’re not actually in motion. More importantly, it constantly self-corrects, based on data from other drivers. “The nature of crowdsourcing is that if you put in a fake accident, the next 10 people are going to report that it’s not there, ” says Julie Mossler, Waze’s head of communications. The company will suspend users they suspect of “tampering with the map.” Read more of this story at Slashdot. 
In winter, ice encroaches on Lake Michigan. In summer, sediment and algal blooms from runoff cloud the waters. But on a perfect day earlier this month, the ice had melted to reveal waters so clear, you could see decades-old shipwrecks lying at the bottom of the lake . Read more…