Tardigrades, aka ‘water bears, ‘ are microscopic organisms that survive in harsh environments from the antarctic to oxygenless space . They are so robust that Japanese scientists froze a group of them for 30 years and successfully revived two specimens. But to understand what makes these tiny creatures so impervious, another group of researchers took a closer look at their genes. By mapping the entire genome of a particularly stress-tolerant tardigrade species, Ramazzottius varieornatus , they found a protein that protects DNA from being irradiated — which could be used to shield humans. As the University of Tokyo researchers describe in the science journal Nature , they took a sample group of human DNA and watched it deteriorate when bombarded with X-rays. But when they allowed some of those to create that tardigrade protein, they only showed half the damage as the control group. Further, those protected cells were still capable of reproducing. As in all specific studies, it’s too early to state how this will translate into treatment, prevention or any dramatic transhumanist strengthening of our species. But the scientists believe more of these proteins, and new applications, are likely lying in wait for more research to uncover. Via: Gizmodo Source: University of Tokyo newsroom
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‘Water Bear’ protein could shield human DNA from radiation
An anonymous reader writes: For the first time data may show that a human being has been successfully rejuvenated by gene therapy, claims Bioviva USA. “In September 2015, then 44 year-old CEO of Bioviva USA Inc. Elizabeth Parrish received two of her own company’s experimental gene therapies: one to protect against loss of muscle mass with age, another to battle stem cell depletion responsible for diverse age-related diseases and infirmities.” Bypassing America’s FDA, the controversial therapies were described by the MIT Technology Review as “do-it-yourself medicine, ” saying it “raises ethical questions about how quickly such treatments should be tested in people and whether they ought to be developed outside the scrutiny of regulators.” “The treatment was originally intended to demonstrate the safety of the latest generation of the therapies, ” reports Bioviva’s web site. “But if early data is accurate, it is already the world’s first successful example of telomere lengthening via gene therapy in a human individual.” Read more of this story at Slashdot.