‘Water Bear’ protein could shield human DNA from radiation

Tardigrades, aka ‘water bears, ‘ are microscopic organisms that survive in harsh environments from the antarctic to oxygenless space . They are so robust that Japanese scientists froze a group of them for 30 years and successfully revived two specimens. But to understand what makes these tiny creatures so impervious, another group of researchers took a closer look at their genes. By mapping the entire genome of a particularly stress-tolerant tardigrade species, Ramazzottius varieornatus , they found a protein that protects DNA from being irradiated — which could be used to shield humans. As the University of Tokyo researchers describe in the science journal Nature , they took a sample group of human DNA and watched it deteriorate when bombarded with X-rays. But when they allowed some of those to create that tardigrade protein, they only showed half the damage as the control group. Further, those protected cells were still capable of reproducing. As in all specific studies, it’s too early to state how this will translate into treatment, prevention or any dramatic transhumanist strengthening of our species. But the scientists believe more of these proteins, and new applications, are likely lying in wait for more research to uncover. Via: Gizmodo Source: University of Tokyo newsroom

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‘Water Bear’ protein could shield human DNA from radiation

Ancient Skeleton Uncovered at the Antikythera Shipwreck

Marine archaeologists have found the partial remains of a 2, 000-year-old skeleton while conducting an excavation at the Antikythera shipwreck, the famous site that yielded the freakishly-advanced Antikythera Mechanism. Incredibly, the ancient remains could still contain traces of DNA. Read more…

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Ancient Skeleton Uncovered at the Antikythera Shipwreck

Who stole the DNA of 14,000 long-lived Italians?

Italian authorities are investigating a biotechnology heist that saw around 14, 000 DNA samples allegedly stolen from a lab in Sardinia. This may not be a simple case of grand larceny, as the samples in question were taken from Italians with exceptionally long lives. Sardinia is one of a handful of “blue zones” with a higher-than-usual proportion of men over the age of 100. The material was gathered as part of a decades-long research investigation into a genetic secret for longevity that was unrelated to diet or environmental factors. The DNA was originally harvested by a publicly-owned lab, Pardo Genetico, which was recently sold off to a Sardinian called Piergiorgio Lorrai. According to the Guardian , Lorrai is a local who wanted to ensure that the genetic information of his countrymen and women weren’t exploited for commercial gain. But it’s not that simple, because through a convoluted series of corporate shenanigans, another company believes it’s the repository’s rightful owner. Of course, that’s less relevant now since the samples have disappeared, and prosecutor Biagio Mazzeo is implying that it might have been an inside job. Analysis of the crime scene reveals that there was no forced entry, although it’s not clear when exactly the alleged theft took place. Perhaps someone’s planning to develop a theme park around clones of centenarians on a Pacific island, John Hammond-style. Or maybe the stuff was grabbed by a sinister billionaire with an interest in living forever, not that we could name any. Via: The Verge Source: Guardian

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Who stole the DNA of 14,000 long-lived Italians?

DNA Resolves 80-Year-Old Mystery Behind Belgian King’s Death 

Controversy has long surrounded the presumed accidental death of Belgium’s King Albert I in 1934, with conspiracy theorists crying murder. Now, 80 years later, forensic geneticists have successfully matched DNA from blood found at the scene of his death with that of two of the late king’s distant relatives, hopefully resolving the mystery once and for all. Read more…

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DNA Resolves 80-Year-Old Mystery Behind Belgian King’s Death 

First Successful Gene Therapy Against Human Aging?

An anonymous reader writes: For the first time data may show that a human being has been successfully rejuvenated by gene therapy, claims Bioviva USA. “In September 2015, then 44 year-old CEO of Bioviva USA Inc. Elizabeth Parrish received two of her own company’s experimental gene therapies: one to protect against loss of muscle mass with age, another to battle stem cell depletion responsible for diverse age-related diseases and infirmities.” Bypassing America’s FDA, the controversial therapies were described by the MIT Technology Review as “do-it-yourself medicine, ” saying it “raises ethical questions about how quickly such treatments should be tested in people and whether they ought to be developed outside the scrutiny of regulators.” “The treatment was originally intended to demonstrate the safety of the latest generation of the therapies, ” reports Bioviva’s web site. “But if early data is accurate, it is already the world’s first successful example of telomere lengthening via gene therapy in a human individual.” Read more of this story at Slashdot.

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First Successful Gene Therapy Against Human Aging?

Laser shines through fly’s skin, controls its heart by activating doped cells

Eliza writes, “A researcher from Lehigh University has invented a light-based pacemaker for fruit flies, and says a human version is ‘not impossible.’ The pacemaker relies on the new technique of ‘optogenetics,’ in which light-sensitive proteins are inserted into certain cells, allowing those cells to be activated by pulses of light. Here, the proteins were inserted into cardiac cells so the researchers could trigger the contractions that produce heartbeats.” (more…)

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Laser shines through fly’s skin, controls its heart by activating doped cells

Wasps Have Injected New Genes Into Butterflies

sciencehabit writes: If you’re a caterpillar, you do not want to meet a parasitic wasp. The winged insect will inject you full of eggs, which will grow inside your body, develop into larvae, and hatch from your corpse. But a new study reveals that wasps have given caterpillars something beneficial during these attacks as well: pieces of viral DNA that become part of the caterpillar genome, protecting them against an entirely different lethal virus. In essence, the wasps have turned caterpillars into genetically modified organisms. Read more of this story at Slashdot.

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Wasps Have Injected New Genes Into Butterflies

What Is the Molecular Clock, Exactly?

In the 150 years since Charles Darwin recognised the kinship of all life, scientists have worked to fulfil his dream of a complete Tree of Life . Today, the methods used to trace the evolutionary branches back through time would exceed Darwin’s expectations. Scientists across a range of biological disciplines use a technique called the molecular clock , where the past is deciphered by reading the stories written in the genes of living organisms. Read more…

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What Is the Molecular Clock, Exactly?

How DNA Could Replace Hard Drives

The capacity of our digital storage devices has skyrocketed in recent years. But there’s one storage medium that still kicks the crap out of our state-of-the-art solid state, and humans didn’t invent it. It’s called DNA. Read more…

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How DNA Could Replace Hard Drives