XPrize winner says its Tricorder is better than ‘Star Trek’

The technology of Gene Roddenberry’s Star Trek looked so far forward it could almost have been used as a visual aide to Arthur C. Clarke’s third law: technology so advanced, it’s indistinguishable from magic. Despite the fictional technological magic of transporters, replicators and warp drive, Qualcomm saw enough potential in the show’s medical tricorder to challenge the world to build one . Now, the Tricorder XPrize finally has a winner in Final Frontier Medical Devices’ DxtER. The result isn’t so much an all-in-one scanner as collection of noninvasive medical-diagnosis gadgets. Even so, its creators claim the DxtER package is better than Star Trek’s fictional tricorder. That isn’t to say that DxtER does more than the show’s magical medical scanner — unlike Star Trek’s tricorder, the winning XPrize entry is actually a small collection of specialized and smart medical devices that interact with the user’s tablet. This includes a compact spirometer that can measure the strength of a patient’s lungs, a Mono test kit, medical-grade heartrate and respiration monitors, and devices like the DxtER Orb, which doubles as a thermometer and stethoscope. These devices can’t scan patients at a microscopic level like Star Trek’s device, but Basil Leaf technology co-founder George Harris says it improves on the show’s tricorder in one key area: It’s designed for patients to use themselves. “One of the things about the tricorder in the show is that it always needed a doctor to interpret the results, ” Harris told Engadget, explaining that DxtER’s companion app helps users understand the medical data DxtER collects. “Our tricorder has the doctor built-in, so it’s both the tricorder and Dr. McCoy together.” He’s not wrong, both from a practical and narrative perspective — characters on Star Trek often didn’t fully understand what a medical scan meant unless the doctor explained it to them. Likewise, the average patient can’t accurately diagnose herself even if she has access to a wealth of medical knowledge. Just ask any hypochondriac with a WebMD addiction. Giving consumers the ability to diagnose themselves at home sounds nice, but it’s bigger than that. Harris says Basil Leaf and Final Frontier Medical Devices are working to make sure every component of the DxtER tricorder kit is FDA-approved — meaning results compiled in the kit’s app could be used by doctors with no need to rerun the same tests at the hospital. “You can take those results and take them to the ER or to your physician or whoever’s helping you, and they can build off those results, ” Harris explained. “They don’t have to start back at square one — they can jump off at that point and move on with their health care.” A consumer version is still probably years away, but Harris says the group is using the $2.5 million it received from winning the XPrize competition to help fund a 500-patient clinical trial, a key step to getting the suite of gadgets approved for use in the US and putting a “Dr. McCoy” in every home that wants one. But Harris is careful to point out that the device isn’t designed to replace a visit to the doctor’s office. “We’re not trying to replace physicians, ” he says. “We’re trying to help you, the consumer, understand their health care and also help those physicians make better decisions for those consumers.”

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XPrize winner says its Tricorder is better than ‘Star Trek’

Snail venom provides a new way to treat chronic pain

The Conus regius’ venom is bad news for its prey, and it’s been proven harmful to humans as well. For instance, a 2009 clinical case describes a diver who had trouble moving his arm for 12 hours after an attack. However, scientists from the University of Utah see hope in the ocean dweller’s powerful venom. In fact, research suggests it could be used to develop a new treatment for chronic pain. This could mean a viable alternative to opioids , which are widely abused in the US. New York officials reported the number of deaths related to Oxycodone, Hydrocodone, and other narcotic medications in the state was 1, 227 in 2013 , nearly four times the amount in 2004. These drugs are addictive because they overstimulate the brain’s reward system with dopamine, which leads to chemical dependence. However, a compound isolated from the venom, Rg1A, works differently, according to The University of Utah . The newly discovered compound blocks a type of pain pathway receptor known as nicotinic acetylcholine receptors (nAChR). This is a non-opioid pathway, meaning that pain relief can be achieved without habit-forming amounts of narcotics. In tests, rodents were treated with chemotherapy drugs, which made them very sensitive to cold and touch. Some of the rats were injected with the compound, and unlike their unmedicated peers, didn’t feel pain. The effects proved to be long-lasting, too. The compound passed through the rats’ bodies in about four hours, but the researchers found that it continued to dull pain a full three days after the injection. This has J. Michael McIntosh, M.D., a professor of psychiatry at the University of Utah Health Sciences, optimistic about Rg1A’s potential not to just treat pain, but to prevent it. “Once chronic pain has developed, it is difficult to treat, ” he said . “This compound offers a potential new pathway to prevent pain from developing in the first place and offer a new therapy to patients who have run out of options.” Current pain-relief drugs work primarily on opioid-based pathways and aren’t effective enough to truly alleviate chronic pain, the university notes. These developments make it possible to treat chronic pain by targeting it through different means. Assuming human testing goes well, we could see the use of narcotics drop and the rise of pain-free patients rise. Source: The University of Utah

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Snail venom provides a new way to treat chronic pain

DNA ‘computers’ could lead to self-activated smart pills

Imagine a pill that knew if you were ill enough to need drugs, and wouldn’t release chemicals if it thought you didn’t need it. That’s the breakthrough that’s been made at Eindhoven University in the Netherlands by a team of researchers ld by Maarten Merkx. The team has harnessed the power of DNA itself to form an organic computer that performs crude calculations on the state of your health. When you get ill, or suffer from a chronic condition, doctors normally prescribe drugs to help you get better, but this is based on a set of generic guidelines. The idea is that a smart pill will be able to offer specific doses, tailored to your needs, reducing the risk of side effects and waste. The computation comes in the form of the DNA, which looks for molecules that it can react with as a form of data-gathering. Put simply, the pill will journey inside your body and sniff the local environment to decide if you need more medicine. Of course, like so many things at the bleeding edge of technology, it’s still early days for this form of treatment, but the potential is exciting. Source: TUE , Nature

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DNA ‘computers’ could lead to self-activated smart pills

Groceries Will Soon Have Practical, Standardized Expiration Dates

We’ve long known that the expiration date on groceries is a mess of different terms that mean absolutely nothing . Now, the Food Marketing Institute and Grocery Manufacturers Association have put together a plan that simplifies the label you’ll see on food. Read more…

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Groceries Will Soon Have Practical, Standardized Expiration Dates

Scientists Develop a Breathalyzer That Detects 17 Diseases With One Breath From a Patient

randomErr quotes a report from Quartz: In the last 10 years, researchers have developed specific sniff tests for diagnosing tuberculosis, hypertension, cystic fibrosis, and even certain types of cancer. A group of global researchers led by Hossam Haick at the Israel Institute of Technology have taken the idea a step further. They’ve built a device — a kind of breathalyzer — that is compact and can diagnose up to 17 diseases from a single breath of a patient. The breathalyzer has an array of specially created gold nanoparticles, which are sized at billionths of a meter, and mixed with similar-sized tubes of carbon. These together create a network that is able to interact differently with each of the nearly 100 volatile compounds that each person breaths out (apart from gases like nitrogen, oxygen, and carbon dioxide). Haick’s team collected 2, 800 breaths from more than 1, 400 patients who were each suffering from at least one of 17 diseases (in three classes: cancer, inflammation, and neurological disorders). Each sample of the disease was then passed through the special breathalyzer, which then produced a dataset of the types of chemicals it could detect and in roughly what quantities. The team then applied artificial intelligence to the dataset to search for patterns in the types of compounds detected and the concentrations they were detected at. As they report in the journal ACS Nano, the data from the breathalyzer could be used to accurately detect that a person is suffering from a unique disease nearly nine out of ten times. Read more of this story at Slashdot.

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Scientists Develop a Breathalyzer That Detects 17 Diseases With One Breath From a Patient

Nevada site bug leaks medical marijuana applicant data

Nevada residents applying to sell medical marijuana got just got an unpleasant surprise. The state’s Department of Health and Human Services has confirmed that a vulnerability in a website portal leaked the data of more than 11, 700 applicants, including their driver’s license and social security numbers. Officials have taken down the relevant site until they fix the flaw, but there’s a concern that fraudsters might have seen the info and used it for malicious purposes. The scale of the leak might be modest. A spokesperson tells ZDNet that the data represented just a “portion” of one data base among several. And when Nevada voted to legalize medical marijuana in 2000, it’s possible that some of the information is outdated. Even so, this underscores a common problem with government data: frequently, agencies are their own worst enemies thanks to avoidable security holes and imperfect policies. Source: ZDNet

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Nevada site bug leaks medical marijuana applicant data

Veterinarian Catches Rare Form of Bird Flu From a Sick Cat Who Maybe Ate a Pigeon

The scariest scene from the movie Contagion. Three days ago, NPR reported that 45 cats were confirmed sick with H7N2, a rare form of avian flu making the leap from birds to felines. Poor kitties. But Thursday morning, the NYC Department of Health confirmed H7N2 has spread from cats to humans, infecting a veterinarian caring for the cats who had tested positive for bird flu. Read more…

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Veterinarian Catches Rare Form of Bird Flu From a Sick Cat Who Maybe Ate a Pigeon

Ancient Bug Discovered in the Heart of Antarctica

Insects aren’t the first thing that come to mind when we think of Antarctica, but as the discovery of a rare Antarctic beetle shows, this frozen continent was quite different millions of years ago. Read more…

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Ancient Bug Discovered in the Heart of Antarctica

US Dementia Rates Drop 24%, New Study Finds

A new study involving more than 21, 000 people across the country finds that dementia rates in people over age 65 fell from 11.6 percent in 2000 to 8.8 percent in 2012 — a decline of 24 percent. CNN reports: The decline in dementia rates translates to about one million fewer Americans suffering from the condition, said John Haaga, director of behavioral and social research at the National Institute on Aging, part of the National Institutes of Health, which funded the new study. Dementia is a general term for a loss of memory or other mental abilities that’s severe enough to interfere with daily life. Alzheimer’s disease, which is believed to be caused by a buildup of plaques and tangles in the brain, is the most common type of dementia. Vascular dementia is the second most common type of dementia and occurs after a stroke. The study, which began in 1992, focuses on people over age 50, collecting data every two years. Researchers conduct detailed interviews with participants about their health, income, cognitive ability and life circumstances. The interviews also include physical tests, body measurements and blood and saliva samples. Although researchers can’t definitively explain why dementia rates are decreasing, Langa said doctors may be doing a better job controlling high blood pressure and diabetes, which can both boost the risk of age-related memory problems. High blood pressure and diabetes both increase the risk of strokes, which kill brain cells, increasing the risk of vascular dementia. Authors of the study found that senior citizens today are better educated than even half a generation ago. The population studied in 2012 stayed in school 13 years, while the seniors studied in 2000 had about 12 years of education, according to the study. People who are better educated may have more intellectually stimulating jobs and hobbies that help exercise their brains, Langa said. The study has been published Monday in JAMA Internal Medicine. Read more of this story at Slashdot.

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US Dementia Rates Drop 24%, New Study Finds

Scientists Discover Antibody That Neutralizes 98% of HIV Strains

An anonymous reader quotes a report from The Inquisitr: The National Institute of Allergy and Infectious Diseases (NIAID) announced this week that a “remarkable” breakthrough has been made in the study of preventing and treating the human immunodeficiency virus (HIV), the virus that leads to acquired immunodeficiency syndrome (AIDS), according to a press release posted on the agency’s official website. The breakthrough centers around the discovery of a powerful antibody named N6 that is highly effective in both binding to the surface of the HIV virus and neutralizing it. The former has proved elusive in the past. “Identifying broadly neutralizing antibodies against HIV has been difficult because the virus rapidly changes its surface proteins to evade recognition by the immune system, ” the press release explains. The antibody was initially discovered in an HIV-positive person and has since proven to potentially neutralize 98 percent of HIV isolates, “including 16 of 20 strains resistant to other antibodies of the same class, ” according to the press release. Researchers have had previous success with other antibodies, but N6 appears to be more effective. The new discovery has potential benefits far beyond preventing and treating HIV as well. Studying exactly how N6 works could potentially lead to breakthroughs in other anti-viral antibodies. “Findings from the current study showed that N6 evolved a unique mode of binding that depends less on a variable area of the HIV envelope known as the V5 region and focuses more on conserved regions, which change relatively little among HIV strains, ” NIAID explains. “This allows N6 to tolerate changes in the HIV envelope, including the attachment of sugars in the V5 region, a major mechanism by which HIV develops resistance to other VRC01-class antibodies. Due to its potency, N6 may offer stronger and more durable prevention and treatment benefits, and researchers may be able to administer it subcutaneously (into the fat under the skin) rather than intravenously. In addition, its ability to neutralize nearly all HIV strains would be advantageous for both prevention and treatment strategies.” Read more of this story at Slashdot.

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Scientists Discover Antibody That Neutralizes 98% of HIV Strains